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Sciences indexed since 1998 submit story | join | login   view all biology business chemistry engineering geography health mathematics society   all     malignant peripheral nerve sheath tumors (mpnst): the mayo clinic experience submitted by gairgin 1 year and 1 month ago malignant peripheral nerve sheath tumors (mpnst) are a rare form of soft tissue sarcoma with few studies reporting on patient outcomes and prognostic variables. viagra 20 mg tabletta A retrospective review of clxxv patients diagnosed with mpnst from 1985 to 21 was performed. buy viagra without prescription Patient, tumor, and treatment characteristics were evaluated to identify prognostic variables. The median age of our study population was 44 years, and 51% were female. Median tumor size was 6 cm, and 61% of patients had high-grade tumors. viagra cheapest Tumors were most commonly located on the extremities (45%), then trunk (34%) and head/neck (19%). The majority of patients underwent surgical resection (95%) and adjuvant treatment with chemotherapy (6%), radiation (42%) or both (22%). Margin status was r in 69%, r1 in 2%, r2 in 9%, and unknown in 2%. The local recurrence rate was 22%, and 5- and 1-year disease-specific survival (dss) were 6% and 45%, respectively. what's best viagra or viagra On univariate analysis, no predictors for local recurrence were identified. Tumor size ≥5 cm, high tumor grade, tumor location, presence of neurofibromatosis type 1, local recurrence, and adjuvant chemotherapy were all associated with dss. On multivariate analysis, size ≥5 cm [hazard ratio (hr) = 6. map of viagra triangle 1, 95% confidence interval (ci) 1. buy cheap viagra 5–25. viagra coupon ], local recurrence (hr = 4. 4, 95% ci 1. 7–11. map of viagra triangle 4), high tumor grade (hr = 3. 8, 95% ci 1. cheap generic viagra 1–13. 2), and truncal location (hr = 3. map of viagra triangle 7, 95% ci 1. generic viagra online 1–12. viagra online without prescription 7) were poor prognostic indicators for dss. High tumor grade and tumor size ≥5 cm predict adverse dss for mpnst. In the context of a multidisciplinary treatment regimen, local recurrence and survival outcomes at 5 and 1 years were better than previously reported for mpnst. 1 dig(s) dig it bury topic: oncology comments (0) who dugg this story? Email this link add your comment please login or signup to leave a comment related stories factors of influence upon overall survival in the treatment of intracranial mpnsts. Review of the literature and report of. where to buy viagra yahoo answers educational

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